{"product_id":"igf-1-lr3-01mg","title":"IGF-1 LR3","description":"\u003cdiv style=\"font-family:Arial,sans-serif;max-width:680px;margin:20px 0 24px;border:1px solid #cbd5e1;border-radius:10px;overflow:hidden;\"\u003e\n\u003cdiv style=\"background:#1a3c5e;color:#fff;padding:12px 16px;\"\u003e\n\u003cstrong style=\"font-size:15px;\"\u003eProtocolo de Dosificación\u003c\/strong\u003e\u003cspan style=\"font-size:12px;margin-left:12px;opacity:0.85;\"\u003e1 vez al día · Subcutáneo o IM\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"background:#e8f0f8;padding:10px 16px;font-size:13px;color:#1a3c5e;\"\u003e\n\u003cstrong\u003eReconstitución:\u003c\/strong\u003e 1 mg + 2 mL BAC Water = 500 mcg\/mL\u003c\/div\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:13px;\"\u003e\n\u003cthead\u003e\u003ctr style=\"background:#2d5a8e;color:#fff;\"\u003e\n\u003cth style=\"padding:8px 10px;text-align:left;\"\u003eFase\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:left;\"\u003eDosis\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:center;\"\u003eUnidades (U-100)\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:center;\"\u003eVolumen (mL)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background:#f8fafc\"\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;\"\u003eInicio\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;font-weight:600;color:#1a3c5e;\"\u003e40 mcg\/día\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e8 unidades\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e0.08 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#ffffff\"\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;\"\u003eEstándar\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;font-weight:600;color:#1a3c5e;\"\u003e60 mcg\/día\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e12 unidades\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e0.12 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f8fafc\"\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;\"\u003eMáximo\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;font-weight:600;color:#1a3c5e;\"\u003e100 mcg\/día\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e20 unidades\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e0.20 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cdiv style=\"background:#f8fafc;padding:8px 16px;font-size:11px;color:#64748b;\"\u003e⚠️ Solo para investigación. Consulta a un profesional de salud calificado antes de uso.\u003c\/div\u003e\n\u003c\/div\u003e\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eQuantity:\u003c\/strong\u003e 0.1 mg per vial\u003cbr\u003e\u003cstrong\u003eSKU:\u003c\/strong\u003e IGL01\u003c\/p\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\u003cp\u003eIGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a modified analog of endogenous IGF-1 engineered with two key changes: an arginine-3 substitution (replacing the native glutamate) and a 13 amino acid N-terminal extension. These modifications dramatically reduce binding affinity to IGF-binding proteins (IGFBPs 1–6), which normally act as transport and regulatory proteins for IGF-1 in circulation.\u003c\/p\u003e\n\u003cp\u003eBy reducing IGFBP binding, IGF-1 LR3 remains in its free, biologically active form significantly longer than native IGF-1, with an estimated half-life of 20–30 hours compared to ~12 minutes for native IGF-1. This extended activity makes it a powerful tool for studying the IGF-1 receptor (IGF-1R) signaling axis, cellular proliferation, differentiation, and anabolic metabolism in research settings.\u003c\/p\u003e\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cp\u003eIGF-1 LR3 has been examined in experimental studies related to:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eIGF-1 receptor (IGF-1R) signaling and AKT\/mTOR pathway studies\u003c\/li\u003e\n\u003cli\u003eProtein synthesis, nitrogen retention, and anabolic metabolism research\u003c\/li\u003e\n\u003cli\u003eReduced IGFBP binding and extended half-life pharmacokinetic research\u003c\/li\u003e\n\u003cli\u003eCell proliferation, differentiation, and anti-apoptotic signaling\u003c\/li\u003e\n\u003cli\u003eMuscle satellite cell activation and myogenesis studies\u003c\/li\u003e\n\u003cli\u003eComparison with native IGF-1 and IGF-1 DES(1-3) variants\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eHandling and Storage (Laboratory Guidance)\u003c\/h2\u003e\n\u003cp\u003eThis product is supplied as a lyophilized peptide powder.\u003c\/p\u003e\n\u003cp\u003eTypical laboratory handling recommendations include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStore at 2–8 °C upon receipt.\u003c\/li\u003e\n\u003cli\u003eProtect from heat, moisture, and direct light.\u003c\/li\u003e\n\u003cli\u003eAvoid excessive agitation of the solution to maintain peptide stability.\u003c\/li\u003e\n\u003cli\u003eReconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.\u003c\/li\u003e\n\u003cli\u003eUse of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFor reconstitution, \u003ca href=\"https:\/\/mvlabs.mx\/pages\/calculadora-de-peptidos\" target=\"_blank\"\u003eCLICK HERE to use the PEPTIDE CALCULATOR\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory protocols may vary depending on the specific research application.\u003c\/p\u003e\u003ch2\u003eQuality Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eResearch grade material\u003c\/li\u003e\n\u003cli\u003eHigh purity (≥99%)\u003c\/li\u003e\n\u003cli\u003eLyophilized for stability\u003c\/li\u003e\n\u003cli\u003eIntended for controlled laboratory environments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDocumentation such as analytical data or certificates of analysis may be available depending on the supplier.\u003c\/p\u003e\u003ch2\u003eImportant Disclaimer – Research Use Only\u003c\/h2\u003e\n\u003cp\u003eThis product is provided strictly for laboratory research and analytical purposes.\u003c\/p\u003e\n\u003cp\u003eIt is not intended for human or animal consumption.\u003c\/p\u003e\n\u003cp\u003eThis compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.\u003c\/p\u003e\n\u003cp\u003eThe purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.\u003c\/p\u003e","brand":"MV Labs","offers":[{"title":"1 mg","offer_id":44816019554419,"sku":"IGL01","price":3400.0,"currency_code":"MXN","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0697\/3577\/6371\/files\/IGF1LR3Details_0b8962ce-fb52-4d6a-8741-529966dff40b.png?v=1780583335","url":"https:\/\/mvlabs.mx\/es\/products\/igf-1-lr3-01mg","provider":"MV Labs","version":"1.0","type":"link"}