{"product_id":"ara-290","title":"ARA-290","description":"\u003cdiv style=\"font-family:Arial,sans-serif;max-width:680px;margin:20px 0 24px;border:1px solid #cbd5e1;border-radius:10px;overflow:hidden;\"\u003e\n\u003cdiv style=\"background:#1a3c5e;color:#fff;padding:12px 16px;\"\u003e\n\u003cstrong style=\"font-size:15px;\"\u003eProtocolo de Dosificación\u003c\/strong\u003e\u003cspan style=\"font-size:12px;margin-left:12px;opacity:0.85;\"\u003e1 vez al día · Subcutáneo\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"background:#e8f0f8;padding:10px 16px;font-size:13px;color:#1a3c5e;\"\u003e\n\u003cstrong\u003eReconstitución:\u003c\/strong\u003e 4 mg + 2 mL BAC Water = 2 mg\/mL\u003c\/div\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:13px;\"\u003e\n\u003cthead\u003e\u003ctr style=\"background:#2d5a8e;color:#fff;\"\u003e\n\u003cth style=\"padding:8px 10px;text-align:left;\"\u003eFase\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:left;\"\u003eDosis\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:center;\"\u003eUnidades (U-100)\u003c\/th\u003e\n\u003cth style=\"padding:8px 10px;text-align:center;\"\u003eVolumen (mL)\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr style=\"background:#f8fafc\"\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;\"\u003eDosis estándar (vial completo)\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;font-weight:600;color:#1a3c5e;\"\u003e4 mg\/día\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e200 unidades\u003c\/td\u003e\n\u003ctd style=\"padding:8px 10px;border-bottom:1px solid #e2e8f0;text-align:center;\"\u003e2.00 mL\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cdiv style=\"background:#f8fafc;padding:8px 16px;font-size:11px;color:#64748b;\"\u003e⚠️ Solo para investigación. Consulta a un profesional de salud calificado antes de uso.\u003c\/div\u003e\n\u003c\/div\u003e\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eQuantity:\u003c\/strong\u003e 10 mg per vial\u003cbr\u003e\u003cstrong\u003eSKU:\u003c\/strong\u003e RA10\u003c\/p\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\u003cp\u003eARA-290 is an 11-amino acid helix B surface peptide (HBSP) derived from the non-erythropoietic portion of erythropoietin (EPO). It is designed to selectively activate the Innate Repair Receptor (IRR) — a tissue-protective heteroreceptor complex consisting of the EPO receptor subunit (EPOR) and the common beta chain (CD131\/βc) — without activating the homodimeric EPOR (EPOR2) complex responsible for erythropoiesis.\u003c\/p\u003e\n\u003cp\u003eThis receptor selectivity allows ARA-290 to deliver the cytoprotective, anti-inflammatory, and neuroregenerative benefits of EPO without the hematopoietic side effects (thrombosis risk, polycythemia) that limit therapeutic EPO use. ARA-290 has undergone clinical trials for painful small fiber neuropathy (SFN) in sarcoidosis patients, where it improved corneal nerve fiber density and pain scores, providing human clinical validation for its neuroprotective mechanism.\u003c\/p\u003e\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cp\u003eARA-290 has been examined in experimental studies related to:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eInnate Repair Receptor (EPOR\/CD131 heterodimer) pharmacology\u003c\/li\u003e\n\u003cli\u003eNeuroprotection and peripheral nerve fiber regeneration studies\u003c\/li\u003e\n\u003cli\u003eNon-hematopoietic EPO signaling and cytoprotection research\u003c\/li\u003e\n\u003cli\u003eSmall fiber neuropathy and chronic pain preclinical models\u003c\/li\u003e\n\u003cli\u003eAnti-inflammatory mechanisms in peripheral tissue injury models\u003c\/li\u003e\n\u003cli\u003eReceptor selectivity: IRR vs homodimeric EPOR (EPOR2) studies\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eHandling and Storage (Laboratory Guidance)\u003c\/h2\u003e\n\u003cp\u003eThis product is supplied as a lyophilized peptide powder.\u003c\/p\u003e\n\u003cp\u003eTypical laboratory handling recommendations include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStore at 2–8 °C upon receipt.\u003c\/li\u003e\n\u003cli\u003eProtect from heat, moisture, and direct light.\u003c\/li\u003e\n\u003cli\u003eAvoid excessive agitation of the solution to maintain peptide stability.\u003c\/li\u003e\n\u003cli\u003eReconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.\u003c\/li\u003e\n\u003cli\u003eUse of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFor reconstitution, \u003ca href=\"https:\/\/mvlabs.mx\/pages\/calculadora-de-peptidos\" target=\"_blank\"\u003eCLICK HERE to use the PEPTIDE CALCULATOR\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory protocols may vary depending on the specific research application.\u003c\/p\u003e\u003ch2\u003eQuality Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eResearch grade material\u003c\/li\u003e\n\u003cli\u003eHigh purity (≥99%)\u003c\/li\u003e\n\u003cli\u003eLyophilized for stability\u003c\/li\u003e\n\u003cli\u003eIntended for controlled laboratory environments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDocumentation such as analytical data or certificates of analysis may be available depending on the supplier.\u003c\/p\u003e\u003ch2\u003eImportant Disclaimer – Research Use Only\u003c\/h2\u003e\n\u003cp\u003eThis product is provided strictly for laboratory research and analytical purposes.\u003c\/p\u003e\n\u003cp\u003eIt is not intended for human or animal consumption.\u003c\/p\u003e\n\u003cp\u003eThis compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.\u003c\/p\u003e\n\u003cp\u003eThe purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.\u003c\/p\u003e","brand":"MV Labs","offers":[{"title":"10 mg","offer_id":44510490525811,"sku":"RA10","price":1700.0,"currency_code":"MXN","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0697\/3577\/6371\/files\/Ara_detail.png?v=1775067867","url":"https:\/\/mvlabs.mx\/products\/ara-290","provider":"MV Labs","version":"1.0","type":"link"}