{"product_id":"botox-botulinum","title":"Botox (Botulinum Toxin A)","description":"\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eQuantity:\u003c\/strong\u003e 100 IU per vial\u003cbr\u003e\u003cstrong\u003eSKU:\u003c\/strong\u003e XT100\u003c\/p\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\u003cp\u003eBotulinum Toxin Type A is a 150 kDa zinc-dependent endopeptidase neurotoxin produced by the anaerobic bacterium Clostridium botulinum. It is internalized into presynaptic motor nerve terminals via receptor-mediated endocytosis, after which its light chain is translocated into the cytoplasm where it cleaves SNAP-25 at a specific Gln197-Arg198 peptide bond within the SNARE complex.\u003c\/p\u003e\n\u003cp\u003eCleavage of SNAP-25 irreversibly disrupts SNARE complex assembly, preventing fusion of acetylcholine-containing synaptic vesicles with the presynaptic membrane and producing neuromuscular blockade lasting 3–6 months until nerve terminal regeneration occurs. Supplied as research-grade material, it is studied in cholinergic neurotransmission, neurotoxin mechanism research, and as a model for targeted synaptic protein cleavage.\u003c\/p\u003e\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cp\u003eBotox (Botulinum Toxin A) has been examined in experimental studies related to:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eSNAP-25 cleavage mechanism and SNARE complex disruption studies\u003c\/li\u003e\n\u003cli\u003eNeuromuscular junction paralysis and cholinergic neurotransmission research\u003c\/li\u003e\n\u003cli\u003eBotulinum toxin serotype mechanism comparison (BoNT\/A through \/G)\u003c\/li\u003e\n\u003cli\u003eCalcium-independent neurotransmitter vesicle fusion inhibition\u003c\/li\u003e\n\u003cli\u003eSpasticity, dystonia, and neuromuscular disorder research models\u003c\/li\u003e\n\u003cli\u003ePeripheral nerve terminal biology and regeneration research\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eHandling and Storage (Laboratory Guidance)\u003c\/h2\u003e\n\u003cp\u003eThis product is supplied as a lyophilized peptide powder.\u003c\/p\u003e\n\u003cp\u003eTypical laboratory handling recommendations include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStore at 2–8 °C upon receipt.\u003c\/li\u003e\n\u003cli\u003eProtect from heat, moisture, and direct light.\u003c\/li\u003e\n\u003cli\u003eAvoid excessive agitation of the solution to maintain peptide stability.\u003c\/li\u003e\n\u003cli\u003eReconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.\u003c\/li\u003e\n\u003cli\u003eUse of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFor reconstitution, \u003ca href=\"https:\/\/mvlabs.mx\/pages\/calculadora-de-peptidos\" target=\"_blank\"\u003eCLICK HERE to use the PEPTIDE CALCULATOR\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLaboratory protocols may vary depending on the specific research application.\u003c\/p\u003e\u003ch2\u003eQuality Information\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eResearch grade material\u003c\/li\u003e\n\u003cli\u003eHigh purity (≥99%)\u003c\/li\u003e\n\u003cli\u003eLyophilized for stability\u003c\/li\u003e\n\u003cli\u003eIntended for controlled laboratory environments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDocumentation such as analytical data or certificates of analysis may be available depending on the supplier.\u003c\/p\u003e\u003ch2\u003eImportant Disclaimer – Research Use Only\u003c\/h2\u003e\n\u003cp\u003eThis product is provided strictly for laboratory research and analytical purposes.\u003c\/p\u003e\n\u003cp\u003eIt is not intended for human or animal consumption.\u003c\/p\u003e\n\u003cp\u003eThis compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.\u003c\/p\u003e\n\u003cp\u003eThe purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.\u003c\/p\u003e","brand":"MV Labs","offers":[{"title":"100 IU","offer_id":44510490067059,"sku":"XT100","price":2500.0,"currency_code":"MXN","in_stock":false}],"url":"https:\/\/mvlabs.mx\/products\/botox-botulinum","provider":"MV Labs","version":"1.0","type":"link"}