Cagrilintide

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: CGL10

Product Overview

Cagrilintide is a long-acting amylin analog peptide under clinical investigation for metabolic research. It is designed to act on amylin receptors — heteroreceptor complexes of the calcitonin receptor (CALCR) with receptor activity-modifying proteins (RAMP1, RAMP2, RAMP3) — which are expressed in the area postrema, nucleus tractus solitarius, and hypothalamus.

By activating these receptors, cagrilintide modulates satiety, slows gastric emptying, and suppresses glucagon secretion. It is frequently studied in combination with GLP-1 receptor agonists such as semaglutide, representing a complementary dual-mechanism approach to metabolic regulation research.

Research Applications

Cagrilintide has been examined in experimental studies related to:

• Amylin receptor (CALCR/RAMP complex) pharmacology
• Satiety signaling and gastric emptying modulation studies
• Glucagon suppression and glucose homeostasis research
• Combination protocols with GLP-1 receptor agonists
• Obesity and type 2 diabetes dual-agonist research models
• Pharmacokinetic studies of long-acting amylin analogs

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.