Acetic Acid Water

Acetic Acid Water (0.6% v/v glacial acetic acid in sterile water for injection) is a standard laboratory diluent specifically formulated for the reconstitution of lyophilized peptides that exhibit poor solubility in neutral aqueous solutions. Many research peptides — including growth hormone-releasing peptides, IGF-1 analogs, and various neuropeptides — are formulated as lyophilized salts that dissolve most efficiently at mildly acidic pH (3.5–5.0).

The 0.6% acetic acid concentration provides a pH of approximately 3.5–4.0, which protonates basic amino acid side chains (Lys, Arg, His) to enhance peptide solubility without causing acid-catalyzed hydrolytic degradation at typical laboratory temperatures. This concentration is based on established pharmaceutical conventions for lyophilized peptide formulation.

Laboratory diluent for reconstituting lyophilized peptides. Store as labeled and keep sealed; draw with sterile technique. Match the diluent and volume to the peptide and your target concentration.