NAD+

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 100 mg per vial
SKU: NJ100

Product Overview

NAD+ (Nicotinamide Adenine Dinucleotide) is a fundamental coenzyme present in all living cells, serving two critical functions: as a redox carrier in cellular energy metabolism (accepting and donating electrons in oxidative phosphorylation), and as a substrate for a growing class of enzymes including sirtuins (SIRT1–7), poly(ADP-ribose) polymerases (PARPs), and CD38/CD157 ectoenzymes.

NAD+ levels decline significantly with age (by up to 50% between young adulthood and middle age) and are associated with impaired mitochondrial function, reduced DNA repair capacity, and metabolic dysfunction. Research into NAD+ supplementation focuses on its potential to activate sirtuins (particularly SIRT1 and SIRT3), promote mitochondrial biogenesis, enhance DNA repair, modulate circadian rhythms, and extend healthspan in model organisms.

Research Applications

NAD+ has been examined in experimental studies related to:

• Sirtuin (SIRT1–7) activation and longevity pathway research
• Mitochondrial biogenesis and oxidative phosphorylation studies
• PARP-mediated DNA repair pathway research
• Cellular senescence, aging, and NAD+ decline models
• Circadian rhythm regulation and metabolic homeostasis research
• CD38 NADase activity and age-related NAD+ depletion studies

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.