CJC-1295 no DAC

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: CND10

Product Overview

CJC-1295 without DAC (also known as Modified GRF 1-29, or Mod-GRF 1-29) is a stabilized truncated analog of GHRH(1-29) incorporating four strategic amino acid substitutions (at positions 2, 8, 15, and 27) that protect against enzymatic degradation by dipeptidyl peptidase IV (DPP-IV) and other proteases. Unlike its DAC counterpart, it retains a physiological half-life of approximately 30 minutes.

This shorter duration mimics the natural pulsatile secretion pattern of endogenous GHRH and is commonly co-administered with GHRP compounds such as Ipamorelin. The combination is studied for producing synergistic GH pulses that more closely mirror physiological GH secretion patterns compared to long-acting analogs.

Research Applications

CJC-1295 no DAC has been examined in experimental studies related to:

• Short-acting GHRH receptor agonism and pulsatile GH release
• DPP-IV-resistant GHRH analog pharmacokinetic studies
• CJC-1295/Ipamorelin combination protocol research
• Comparison of pulsatile vs continuous GH stimulation models
• IGF-1 axis modulation and downstream signaling
• GHRH analog proteolytic stability research

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.