Melatonin

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: MT10

Product Overview

Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine neurohormone synthesized from serotonin (via AANAT and HIOMT enzymes) primarily in the pineal gland, with production tightly controlled by light exposure through the suprachiasmatic nucleus (SCN). Its rhythmic nocturnal secretion is the primary biochemical signal communicating darkness and time-of-day information to the body.

Melatonin acts on MT1 and MT2 G-protein coupled receptors in the SCN, pituitary, and peripheral tissues to synchronize circadian rhythms, promote sleep onset, and regulate seasonal biology. Beyond chronobiology, melatonin is one of the most potent endogenous antioxidants known — directly scavenging free radicals and upregulating antioxidant enzymes (SOD, GPx, catalase). Research also examines its roles in mitochondrial protection, immune modulation, and anti-tumor biology.

Research Applications

Melatonin has been examined in experimental studies related to:

• MT1/MT2 receptor pharmacology and circadian rhythm synchronization
• Sleep onset, architecture, and chronobiology research
• Direct free radical scavenging and antioxidant enzyme upregulation
• Mitochondrial membrane protection and oxidative stress models
• Immune modulation and anti-inflammatory cytokine regulation
• Anti-tumor and oncostatic activity research models

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.