Sermorelin

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: SMO10

Product Overview

Sermorelin is a synthetic analog of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH 1-29-NH2). It is the shortest fully active fragment of GHRH capable of binding to pituitary GHRH receptors and stimulating GH secretion through physiological feedback mechanisms of the hypothalamic-pituitary axis.

Unlike exogenous GH administration, sermorelin acts by stimulating the pituitary gland itself to produce and secrete GH, preserving the natural negative feedback loops that regulate GH levels. This property makes it a valuable tool in research examining age-related GH decline, GH deficiency models, and the pharmacodynamics of pituitary GH secretion.

Research Applications

Sermorelin has been examined in experimental studies related to:

• Pituitary GHRH receptor stimulation and GH secretion studies
• Preservation of hypothalamic-pituitary feedback mechanism research
• Age-related GH decline and GH deficiency models
• Pharmacodynamics of pulsatile GH secretion research
• Comparison of sermorelin with synthetic GHRH analogs (CJC-1295, tesamorelin)
• IGF-1 axis response to physiological GH stimulation

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.