Tesamorelin

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: TSM10

Product Overview

Tesamorelin is a stabilized synthetic analog of GHRH in which the native peptide is conjugated to a trans-3-hexenoic acid moiety at the N-terminus, protecting it from enzymatic degradation and enhancing its stability. It is the only GHRH analog with FDA approval (for HIV-associated lipodystrophy), making it one of the most clinically validated GHRH analogs available for research.

Tesamorelin acts on pituitary GHRH receptors to stimulate GH release, which subsequently reduces visceral adipose tissue (VAT) through enhanced lipolysis. It is studied in models of metabolic syndrome, visceral obesity, and lipodystrophy, and has demonstrated significant reductions in VAT in multiple clinical trials.

Research Applications

Tesamorelin has been examined in experimental studies related to:

• Visceral adipose tissue reduction research and mechanisms
• HIV-associated lipodystrophy and metabolic syndrome models
• GHRH receptor agonism and pituitary GH axis studies
• N-terminal stabilization strategies for peptide half-life extension
• IGF-1 axis and hepatic glucose metabolism research
• Comparison with other GHRH analogs in clinical lipid metabolism

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.