AOD9604

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: 10AD

Product Overview

AOD9604 (Anti-Obesity Drug 9604) is a modified synthetic fragment of human growth hormone corresponding to amino acids 177–191, with a tyrosine residue added at the N-terminus (Tyr-hGH177-191). It was specifically engineered to preserve the lipolytic activity of the HGH C-terminal region while eliminating the growth-promoting, IGF-1-stimulating, and insulin resistance-inducing effects associated with full-length HGH.

AOD9604 activates the beta-3 adrenergic receptor (β3-AR) on adipocytes to stimulate intracellular lipolysis via cAMP elevation, without stimulating IGF-1 production or inducing hyperglycemia. It has received GRAS (Generally Recognized As Safe) status from the FDA for food and supplement applications and was evaluated in multiple clinical trials for obesity treatment, providing a strong human safety data foundation for research use.

Research Applications

AOD9604 has been examined in experimental studies related to:

• Beta-3 adrenergic receptor (β3-AR) activation and cAMP-mediated lipolysis
• Selective adipose tissue fat oxidation without IGF-1 stimulation
• HGH C-terminal fragment pharmacology and receptor specificity
• Obesity, body composition, and adiposity research models
• Insulin sensitivity preservation studies vs full-length HGH
• cAMP-mediated metabolic signaling in adipocytes

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.