CJC-1295 with DAC

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 5 mg per vial
SKU: CD5

Product Overview

CJC-1295 with DAC (Drug Affinity Complex) is a modified analog of GHRH (growth hormone-releasing hormone) featuring a maleimidoproprionic acid (MPA) side chain that enables covalent binding to endogenous albumin through a Michael addition reaction. This albumin binding dramatically extends the compound's plasma half-life to approximately 7–10 days, enabling weekly dosing protocols in research settings.

By continuously stimulating pituitary GHRH receptors over an extended period, CJC-1295 DAC produces sustained elevations in GH and IGF-1 levels. It is studied as a model compound for long-acting GHRH receptor agonism and is often compared with shorter-acting GHRH analogs to evaluate the pharmacological consequences of continuous vs pulsatile GH stimulation.

Research Applications

CJC-1295 with DAC has been examined in experimental studies related to:

• Long-acting GHRH receptor agonism and sustained GH axis stimulation
• Albumin-binding drug delivery mechanism studies
• Sustained IGF-1 production research
• Comparison of continuous vs pulsatile GH release pharmacology
• Weekly dosing protocol research models
• Half-life extension technology in peptide therapeutics

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.