Snap-8

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: NP810

Product Overview

Snap-8 (Acetyl Glutamyl Heptapeptide-3, SNAP-8) is a synthetic octapeptide analog of the N-terminal domain of SNAP-25 (synaptosomal-associated protein of 25 kDa), one of the three core proteins of the SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment protein REceptor) complex that mediates calcium-triggered neurotransmitter vesicle fusion at synaptic junctions.

By presenting a competing peptide that mirrors the SNAP-25 N-terminal domain, Snap-8 interferes with SNARE complex assembly, reducing the efficiency of acetylcholine-containing vesicle fusion at neuromuscular junctions. In cosmetic research, this translates to studied modulation of facial muscle contraction intensity. It has a longer chain than Argireline (Acetyl Hexapeptide-3) and is studied for potentially broader SNARE complex interference in neuromuscular junction pharmacology.

Research Applications

Snap-8 has been examined in experimental studies related to:

• SNARE complex assembly interference and neuromuscular junction pharmacology
• Acetylcholine vesicle fusion modulation at synaptic terminals
• Comparison with Argireline (Acetyl Hexapeptide-3) mechanism studies
• Topical cosmetic anti-wrinkle and myorelaxant research
• SNAP-25 protein interaction and synaptic biology research
• Facial muscle contraction modulation in aesthetic dermatology research

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.