Thymosin Alpha-1

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: TA10

Product Overview

Thymosin Alpha-1 (Tα1) is a 28-amino acid acetylated peptide naturally secreted by thymic epithelial cells that plays a central role in T-cell maturation, differentiation, and immune regulation. It acts on multiple pattern recognition receptors including Toll-like receptors TLR-2 and TLR-9, activating dendritic cells and monocytes to produce pro-immune cytokines.

Thymosin Alpha-1 is approved in numerous countries (under the brand name Zadaxin) for the treatment of hepatitis B, hepatitis C, and as an immunostimulant in immunocompromised patients, giving it one of the strongest clinical validation profiles of any research peptide. Its mechanisms are studied in the context of T-helper cell activation, NK cell function, antiviral defense, and age-related immune decline.

Research Applications

Thymosin Alpha-1 has been examined in experimental studies related to:

• T-cell maturation, differentiation, and Th1/Th2 balance research
• TLR-2/TLR-9 innate immune signaling and dendritic cell activation
• NK cell function and cytotoxic immune response studies
• Antiviral immune response and hepatitis models
• Age-related immune senescence and immunosenescence research
• Regulatory T-cell modulation and autoimmunity models

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.