KissPeptin-10

Purity: ≥99% HPLC
Format: Lyophilized powder
Quantity: 10 mg per vial
SKU: KS10

Product Overview

KissPeptin-10 (Kp-10) is the shortest bioactive fragment of the kisspeptin family — a group of peptide hormones encoded by the KISS1 gene that range from Kp-10 to Kp-54 in length. It acts as the endogenous ligand for the kisspeptin receptor (KISS1R, also called GPR54), a Gq/11-coupled receptor expressed in hypothalamic GnRH neurons and in peripheral reproductive tissues.

The kisspeptin/KISS1R system represents the primary gating mechanism controlling GnRH pulse secretion from the hypothalamus, effectively functioning as the "master switch" of reproductive physiology. Research applications include the study of GnRH pulse generation, puberty onset mechanisms, sex steroid negative/positive feedback, and gonadotropin secretion in normal and pathological reproductive states.

Research Applications

KissPeptin-10 has been examined in experimental studies related to:

• KISS1R (GPR54) receptor pharmacology and Gq/11 signaling studies
• GnRH pulse generation and hypothalamic control mechanisms
• Puberty onset, pubertal delay, and precocious puberty research
• Sex steroid feedback regulation and neuroendocrinology
• Fertility, hypogonadism, and anovulation research models
• LH/FSH secretion dynamics and gonadotropin axis research

Handling and Storage (Laboratory Guidance)

This product is supplied as a lyophilized peptide powder.

Typical laboratory handling recommendations include:

• Store at 2–8 °C upon receipt.
• Protect from heat, moisture, and direct light.
• Avoid excessive agitation of the solution to maintain peptide stability.
• Reconstitution, if required for laboratory experiments, should be performed using appropriate sterile laboratory techniques.
• Use of acetic acid water (0.6%) or sterile bacteriostatic water is recommended for peptides with low aqueous solubility.

For reconstitution, CLICK HERE to use the PEPTIDE CALCULATOR

Laboratory protocols may vary depending on the specific research application.

Quality Information

• Research grade material
• High purity (≥99%)
• Lyophilized for stability
• Intended for controlled laboratory environments

Documentation such as analytical data or certificates of analysis may be available depending on the supplier.

Important Disclaimer – Research Use Only

This product is provided strictly for laboratory research and analytical purposes.

It is not intended for human or animal consumption.

This compound: is not a drug, is not a dietary supplement, and has not been approved by regulatory authorities such as the FDA, EMA, or other agencies for medical use.

The purchaser agrees that the product will be handled only by qualified professionals in appropriate research facilities and in accordance with all applicable laws and regulations. The supplier assumes no liability for misuse or improper handling of this material.