HCG

Human Chorionic Gonadotropin (HCG) is a glycoprotein heterodimeric hormone composed of an alpha subunit (shared with LH, FSH, and TSH) and a unique beta subunit that confers biological specificity. It binds with high affinity to the LH/CG receptor (LHCGR), activating the same downstream cAMP/PKA signaling pathway as luteinizing hormone (LH).

In males, HCG stimulates Leydig cells to produce testosterone and supports spermatogenesis, making it a key tool in studies of testicular steroidogenesis and the hypothalamic-pituitary-gonadal (HPG) axis. In females, it triggers ovulation and supports corpus luteum function. Research applications include fertility biology, steroidogenesis studies, and HPG axis pharmacology.

• LH/CG receptor (LHCGR) pharmacology and cAMP/PKA signaling
• Testicular steroidogenesis and testosterone production research
• Leydig cell function and gonadotropin receptor studies
• Ovarian stimulation, follicular development, and ovulation research
• HPG axis dynamics and gonadotropin feedback research
• Fertility protocol and hypogonadism preclinical models

Dose levels referenced by the MVLabs peptide calculator, shown for research reference only:

Dosed in international units (IU), not mg. Reconstitute per vial IU. Use the calculator only for mg-based compounds.

Research reference only — not dosing guidance for human use. Use the calculator for other vials or volumes.

Supplied as a lyophilized powder. Store at 2–8 °C on receipt; protect from heat, light and moisture, and avoid excessive agitation. If reconstitution is required for laboratory work, use sterile technique — bacteriostatic water, or 0.6% acetic acid for low-solubility peptides. Protocols vary by research application.